Article
Interaction of cytochrome P4501A1 genotypes with other risk factors and susceptibility to lung cancer.
Mutation research - 1 Mar 2008
Shah Parag P, Singh Arvind P, Singh Madhu, Mathur Neeraj, Pant Mohan C, Mishra Bhartendu N, Parmar Devendra
Abstract excerpt
Lung cancer is the most common cause of death throughout the world with cigarette smoking being established as the major etiological factor in lung cancer. Since not much information is available regarding the polymorphism in drug metabolizing enzymes and lung cancer risk in the Indian population, the present case-control study attempted to investigate the association of polymorphisms in cytochrome P450 1A1...
Topics
- Adult
- Alcohol Drinking
- Carcinoma, Squamous Cell
- Case-Control Studies
- Cytochrome P-450 CYP1A1
- Disease Susceptibility
- Genotype
- Glutathione Transferase
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Polymorphism, Genetic
- Risk Factors
- Smoking
- Tobacco Use Disorder