Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Independent and Interactive Effect of CYPs and GSTs Genetic Variants and Tobacco Smoking on the Risk of Non-Small Cell Lung Carcinoma.

Archives of medical research - 1 Oct 2021

Pathak Anumesh K, Husain Nuzhat, Kant Surya, Bala Lakshmi

Abstract excerpt

BACKGROUND: CYP and GST gene families detoxify tobacco carcinogens and have been linked to the risk of non-small cell lung carcinoma (NSCLC). AIM: Independent and combined effects of CYP and GST genetic variations and smoking on the risk of non-small cell lung carcinoma (NSCLC) and its sub-histological types. METHODS: We modelled an epistatic interaction via the effects of particular genotypes in two genes as OR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Cytochrome P-450 CYP2A6

Share to Cytochrome P-450 Enzyme System

Share to Glutathione Transferase

Share to Lung Neoplasms

Share to Tobacco Smoking

Source

Identifiers

PMID: 34092421
DOI: 10.1016/j.arcmed.2021.05.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Independent and Interactive Effect of CYPs and GSTs Genetic Variants and Tobacco Smoking on the Risk of Non-Small Cell Lung Carcinoma.PMID 34092421Read ↗

[Combined effects of genetic polymorphisms in cytochrome P450s and GSTM1 on lung cancer susceptibility].Semantic proximity Read ↗

The effect of CYP, GST, and SULT polymorphisms and their interaction with smoking on the risk of hepatocellular carcinoma.Semantic proximity Read ↗

Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update of the GSEC study.Semantic proximity Read ↗

Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers.Semantic proximity Read ↗

Interaction of the CYP1A1 gene polymorphism and smoking in non-small cell lung cancer susceptibility.Semantic proximity Read ↗

Synergistic association of PTGS2 and CYP2E1 genetic polymorphisms with lung cancer risk in northeastern Chinese.Semantic proximity Read ↗

Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a north indian population.Semantic proximity Read ↗

Genetic polymorphisms of phase I and phase II metabolic enzymes as modulators of lung cancer susceptibility.Semantic proximity Read ↗

[Individual predisposition to lung neoplasm--the role of genes involved in metabolism of carcinogens].Semantic proximity Read ↗

Combined effect of GSTM1, GSTT1 and GSTP1 polymorphisms on histological subtypes of lung cancer.Semantic proximity Read ↗

Multiple analytical approaches reveal distinct gene-environment interactions in smokers and non smokers in lung cancer.Semantic proximity Read ↗

Effects of glutathione S-transferases GSTM1 and GSTT1 genotypes on lung cancer risk in smokers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.