Article
Risk of dementia in parents of probands with and without the apolipoprotein E4 allele. The EVA study.
Journal of epidemiology and community health - 1 Jul 1999
Danet S, Brousseau T, Richard F, Amouyel P, Berr C
Abstract excerpt
STUDY OBJECTIVE: Age, family history of dementia and the epsilon 4 allele of the apolipoprotein E gene have been associated with Alzheimer's disease (AD). Considering the strength of APOE-epsilon 4 as a genetic risk factor for AD, this factor might explain a large part of the association between AD and a family history of dementia. Therefore, in the general population, a higher frequency of dementia should be...
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