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Article

Characterization of the mus308 gene in Drosophila melanogaster.

Genetics - 1 Jan 1993

Leonhardt E A, Henderson D S, Rinehart J E, Boyd J B

Abstract excerpt

Among the available mutagen-sensitive mutations in Drosophila, those at the mus308 locus are unique in conferring hypersensitivity to DNA cross-linking agents but not to monofunctional agents. Those mutations are also associated with an elevated frequency of chromosomal aberrations, altered DNA metabolism and the modification of a deoxyribonuclease. This spectrum of phenotypes is shared with selected mammalian...

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Identifiers

PMID: 8417992
DOI: 10.1093/genetics/133.1.87
PMCID: PMC1205301

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Characterization of the mus308 gene in Drosophila melanogaster.PMID 8417992Read ↗

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A large-scale screen for mutagen-sensitive loci in Drosophila.Semantic proximity Read ↗

The Zuker collection: a resource for the analysis of autosomal gene function in Drosophila melanogaster.Semantic proximity Read ↗

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A Short History and Description of Drosophila melanogaster Classical Genetics: Chromosome Aberrations, Forward Genetic Screens, and the Nature of Mutations.Semantic proximity Read ↗

A cytogenetic analysis of chromosomal region 31 of Drosophila melanogaster.Semantic proximity Read ↗

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The Drosophila mus 308 gene product, implicated in tolerance of DNA interstrand crosslinks, is a nuclear protein found in both ovaries and embryos.Semantic proximity Read ↗

Genetic and molecular analysis of hyperplastic discs, a gene whose product is required for regulation of cell proliferation in Drosophila melanogaster imaginal discs and germ cells.Semantic proximity Read ↗

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