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Article

Transformation blocks differentiation-induced inhibition of serum response factor interactions with serum response elements.

Cancer research - 1 Aug 1999

Ding W, Witte M M, Scott R E

Abstract excerpt

The differentiation of nontransformed 3T3T mesenchymal stem cells is a multistep process that is associated with the progressive repression of mitogenic responsiveness to serum growth factors that ultimately results in expression of the terminally differentiated adipocyte phenotype. The repression of serum-induced mitogenesis by differentiation correlates with repression of the serum-inducible transcription of...

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Share to Adipocytes
Share to Antigens, Polyomavirus Transforming
Share to Cell Transformation, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, fos

Share to Genes, jun

Share to Serum Response Factor

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Source

Identifiers

PMID: 10446998

Genes

SRF
CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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