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Article

Ternary complex factor-serum response factor complex-regulated gene activity is required for cellular proliferation and inhibition of apoptotic cell death.

Molecular and cellular biology - 1 Dec 2004

Vickers Elaine R, Kasza Aneta, Kurnaz Isil Aksan, Seifert Anne, Zeef Leo A H, O'donnell Amanda, Hayes Andy, Sharrocks Andrew D

Abstract excerpt

Members of the ternary complex factor (TCF) subfamily of the ETS-domain transcription factors are activated through phosphorylation by mitogen-activated protein kinases (MAPKs) in response to a variety of mitogenic and stress stimuli. The TCFs bind and activate serum response elements (SREs) in the promoters of target genes in a ternary complex with a second transcription factor, serum response factor (SRF). The...

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Identifiers

PMID: 15542842
DOI: 10.1128/MCB.24.23.10340-10351.2004
PMCID: PMC529045

Genes

SRF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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