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Article

The Werner syndrome protein is involved in RNA polymerase II transcription.

Molecular biology of the cell - 1 Aug 1999

Balajee A S, Machwe A, May A, Gray M D, Oshima J, Martin G M, Nehlin J O, Brosh R, Orren D K, Bohr V A

Abstract excerpt

Werner syndrome (WS) is a human progeroid syndrome characterized by the early onset of a large number of clinical features associated with the normal aging process. The complex molecular and cellular phenotypes of WS involve characteristic features of genomic instability and accelerated replicative senescence. The gene involved (WRN) was recently cloned, and its gene product (WRNp) was biochemically characterized...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 10436020
DOI: 10.1091/mbc.10.8.2655
PMCID: PMC25497

Genes

WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Werner syndrome protein is involved in RNA polymerase II transcription.PMID 10436020Read ↗

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