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Article

Spo76p is a conserved chromosome morphogenesis protein that links the mitotic and meiotic programs.

Cell - 23 Jul 1999

van Heemst D, James F, Pöggeler S, Berteaux-Lecellier V, Zickler D

Abstract excerpt

Spo76p is conserved and related to the fungal proteins Pds5p and BIMD and the human AS3 prostate proliferative shutoff-associated protein. Spo76p localizes to mitotic and meiotic chromosomes, except at metaphase(s) and anaphase(s). During meiotic prophase, Spo76p assembles into strong lines in correlation with axial element formation. As inferred from spo76-1 mutant phenotypes, Spo76p is required for sister...

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PMID: 10428037
DOI: 10.1016/s0092-8674(00)81020-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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