Article
Mechanism and control of meiotic recombination initiation.
Current topics in developmental biology - 1 Jan 2001
Keeney S
Abstract excerpt
Homologous recombination is essential during meiosis in most sexually reproducing organisms. In budding yeast, and most likely in other organisms as well, meiotic recombination proceeds via the formation and repair of DNA double-strand breaks (DSBs). These breaks appear to be formed by the Spo11 protein, with assistance from a large number of other gene products, by a topoisomerase-like transesterase mechanism....
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