Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human phenol sulfotransferases SULT1A2 and SULT1A1: genetic polymorphisms, allozyme properties, and human liver genotype-phenotype correlations.

Biochemical pharmacology - 15 Aug 1999

Raftogianis R B, Wood T C, Weinshilboum R M

Abstract excerpt

Phenol sulfotransferases (PSTs or phenol SULTs) catalyze the sulfate conjugation of phenolic drugs, xenobiotics, and monoamines. Two human PST isoforms have been defined biochemically, a thermostable (TS), or phenol-preferring, and a thermolabile (TL), or monoamine-preferring form. Pharmacogenetic studies showed that levels of both TS PST activity and TS PST thermal stability (an indirect measure of variation in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arylsulfotransferase
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to COS Cells

Share to Isoenzymes

Share to Polymorphism, Genetic

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 10413297
DOI: 10.1016/s0006-2952(99)00145-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human phenol sulfotransferases SULT1A2 and SULT1A1: genetic polymorphisms, allozyme properties, and human liver genotype-phenotype correlations.PMID 10413297Read ↗

Phenol sulfotransferase pharmacogenetics in humans: association of common SULT1A1 alleles with TS PST phenotype.Semantic proximity Read ↗

Characterization of human liver thermostable phenol sulfotransferase (SULT1A1) allozymes with 3,3',5-triiodothyronine as the substrate.Semantic proximity Read ↗

Genetic polymorphisms in human liver phenol sulfotransferases involved in the bioactivation of N-hydroxy derivatives of carcinogenic arylamines and heterocyclic amines.Semantic proximity Read ↗

A simple colorimetric assay for phenotyping the major human thermostable phenol sulfotransferase (SULT1A1) using platelet cytosols.Semantic proximity Read ↗

Pharmacogenetics of soluble sulfotransferases (SULTs).Semantic proximity Read ↗

Common genetic polymorphisms in the 5'-flanking region of the SULT1A1 gene: haplotypes and their association with platelet enzymatic activity.Semantic proximity Read ↗

Molecular biology of the human phenol sulfotransferase gene family.Semantic proximity Read ↗

Relationship of phenol sulfotransferase activity (SULT1A1) genotype to sulfotransferase phenotype in platelet cytosol.Semantic proximity Read ↗

SULT genetic polymorphisms: physiological, pharmacological and clinical implications.Semantic proximity Read ↗

Sulfotransferase (SULT) 1A1 polymorphic variants *1, *2, and *3 are associated with altered enzymatic activity, cellular phenotype, and protein degradation.Semantic proximity Read ↗

Structure, Function and Polymorphism of Human Cytosolic SulfotransferasesSemantic proximity Read ↗

Sulfotransferase genetic variation: from cancer risk to treatment response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.