Article
Phenol sulfotransferase pharmacogenetics in humans: association of common SULT1A1 alleles with TS PST phenotype.
Biochemical and biophysical research communications - 9 Oct 1997
Raftogianis R B, Wood T C, Otterness D M, Van Loon J A, Weinshilboum R M
Abstract excerpt
The phenol sulfotransferases (PSTs) catalyze the sulfation of both small planar phenols and phenolic monoamines. Three highly homologous PST genes, SULT1A1, SULT1A2, and SULT1A3, are known to exist in humans. The prototypic biochemical phenotype associated with the enzyme encoded by SULT1A1 is th...
Topics
- Alleles
- Arylsulfotransferase
- Base Sequence
- Blood Platelets
- Chromosome Mapping
- Enzyme Stability
- Humans
- Isoenzymes
- Molecular Sequence Data
- Pharmacogenetics
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Genetic