Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms.

Genes and immunity - 1 May 2001

Ligers A, Teleshova N, Masterman T, Huang W X, Hillert J

Abstract excerpt

CTLA-4, expressed mainly on activated T cells, helps maintain, through its inhibitory function, immune-system homeostasis. Polymorphisms in the CTLA-4 gene (CTLA4) are known to be important in several autoimmune diseases, including multiple sclerosis (MS). Here, we have performed genotyping for C...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abatacept
Share to Antigens, CD
Share to Antigens, Differentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CTLA-4 Antigen

Share to Immunoconjugates

Share to Immunosuppressive Agents

Share to Multiple Sclerosis

Share to Myasthenia Gravis

Source

Identifiers

PMID: 11426323
DOI: 10.1038/sj.gene.6363752

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11426323-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms.PMID 11426323Read ↗

The CTLA-4 gene is associated with multiple sclerosis.Semantic proximity Read ↗

CTLA4 promoter and exon 1 dimorphisms in multiple sclerosis.Semantic proximity Read ↗

Genomic regulation of CTLA4 and multiple sclerosis.Semantic proximity Read ↗

CDS1 and promoter single nucleotide polymorphisms of the CTLA-4 gene in human myasthenia gravis.Semantic proximity Read ↗

CTLA-4 gene polymorphisms (-318C/T, +49A/G, +6230A/G) in Iranian patients with multiple sclerosis.Semantic proximity Read ↗

No evidence for association of CTLA-4 gene polymorphisms with the risk of developing multiple sclerosis: a meta-analysis.Semantic proximity Read ↗

CTLA4 dimorphisms and the multiple sclerosis phenotype.Semantic proximity Read ↗

The CTLA-4 gene polymorphisms are associated with CTLA-4 protein expression levels in multiple sclerosis patients and with susceptibility to disease.Semantic proximity Read ↗

Sex specifically associated promoter polymorphism in multiple sclerosis affects interleukin 4 expression levels.Semantic proximity Read ↗

CTLA-4 gene and the susceptibility of multiple sclerosis: an updated meta-analysis study including 12,916 cases and 15,455 controls.Semantic proximity Read ↗

CTLA-4 +49 A/G and -318 C/T polymorphisms and susceptibility to multiple sclerosis: a meta-analysis.Semantic proximity Read ↗

CTLA4 exon 1 and promoter polymorphisms in patients with multiple sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.