Article
Overexpression of protein kinase C epsilon in astroglial brain tumor derived cell lines and primary tumor samples.
1 Aug 1999
Abstract excerpt
Prognosis for astroglial brain tumors that are not amenable to surgical resection remains poor. Consequently, a need to identify new cellular targets and chemotherapeutics for the treatment of astroglial tumors remains. Important reports indicate that human astroglial cell lines express higher protein kinase C (PKC) activity in comparison to normal astrocytes. PKC designates a family of kinases that regulate many...
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