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Article

Differential activation of phospholipases by mitogenic EGF and neurogenic PDGF in immortalized hippocampal stem cell lines.

Journal of neurochemistry - 1 Sept 2001

Sung J Y, Lee S Y, Min D S, Eom T Y, Ahn Y S, Choi M U, Kwon Y K, Chung K C

Abstract excerpt

In several neuronal systems, nerve growth factor (NGF) and platelet-derived growth factor (PDGF) act as neurogenic agents, whereas epidermal growth factor (EGF) acts as a mitogenic agent. Hippocampal stem cell lines (HiB5) immortalized by the expression of a temperature-sensitive SV40 large T antigen also respond differentially to EGF and PDGF. While EGF treatment at the permissive temperature induces...

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Source

Identifiers

PMID: 11553678
DOI: 10.1046/j.1471-4159.2001.00491.x

Genes

EGF
NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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