Article
[Effect of PCBs on mouse lung tumorigenesis induced by 1-nitropyrene: a preliminary report].
Fukuoka igaku zasshi = Hukuoka acta medica - 1 May 1999
Nakanishi Y, Bai F, Takayama K, Pei X H, Inoue K, Osaki S, Izumi M, Takaki Y, Hara N, Tokiwa H, Masuda Y
Abstract excerpt
We have analyzed the effect of polychlorinated biphenyls (PCB, Kanechlor-400) on 1-nitropyrene (1-NP) induced lung tumor. Male A/J mice (6 weeks old) were used for the experiment. A total of 2.5 mg/kg PCB was administered intraperitoneally (PCB group), a total of 0.38 mmol/kg 1-NP was administered intraperitoneally for 17 times (1-NP group), PCB was administered followed by i.p. injection of 1-NP (PCB + 1-NP...
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