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Article

Mutations of lysophosphatidic acid receptor-1 gene during progression of lung tumors in rats.

Biochemical and biophysical research communications - 16 Jan 2009

Yamada Takanori, Obo Yumi, Furukawa Mami, Hotta Mayuko, Yamasaki Ayako, Honoki Kanya, Fukushima Nobuyuki, Tsujiuchi Toshifumi

Abstract excerpt

Lysophosphatidic acid (LPA) is a bioactive phospholipid that stimulates cell proliferation, migration, and protects cells from apoptosis. It interacts with specific G protein-coupled transmembrane receptors. In this study, mutations of lysophosphatidic acid receptor-1 (LPA1) gene were investigated to clarify the possible molecular mechanisms underlying the development of lung tumors induced by...

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Source

Identifiers

PMID: 19026987
DOI: 10.1016/j.bbrc.2008.11.044

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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