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Article

Alterations of the LKB1 gene in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2010

Tajiri Masaki, Wakabayashi Naoko, Tsujino Megumu, Fujii Minako, Okabe Kyoko, Honoki Kanya, Tsujiuchi Toshifumi

Abstract excerpt

OBJECTIVE: Germ line mutations of the LKB1 gene cause the autosomal dominant Peutz-Jeghers syndrome (PJS), and PJS has also been associated with an increased risk of developing cancers, suggesting LKB1 may act as a tumor suppressor in PJS. By contrast, LKB1 mutations are rare events in most spora...

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Identifiers

PMID: 20616618
DOI: 10.1159/000305355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20616618-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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