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Article

Polychlorinated biphenyls promote 1-nitropyrene-induced lung tumorigenesis without the induction of K-ras gene mutation in A/J mice.

Teratogenesis, carcinogenesis, and mutagenesis - 1 Jan 2001

Nakanishi Y, Bai F, Inoue K, Takayama K, Pei X H, Harada T, Izumi M, Kimotsuki K, Tokiwa H, Hara N

Abstract excerpt

Although the effects of polychlorinated biphenyls (PCBs) on human lung carcinogenesis are suggested from the massive PCBs poisoning that occurred in Japan designated "Yusho," the detailed molecular mechanism are unknown. 1 nitropyrene (1-NP), an ubiquitous and abundant environmental pollutant, is...

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PMID: 11746253
DOI: 10.1002/tcm.1027

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CGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11746253-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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