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Article

Ki-ras mutation and cell proliferation of lung lesions induced by 1-nitropyrene in A/J mice.

Molecular carcinogenesis - 1 Aug 1998

Bai F, Nakanishi Y, Takayama K, Pei X H, Tokiwa H, Hara N

Abstract excerpt

In this study, lung lesions were found in male A/J mice 24 wk after intraperitoneal injection of 1-nitropyrene (1-NP). The lesions were classified into three categories: alveolar/bronchiolar hyperplasia, adenoma, and adenocarcinoma. The proliferation kinetics of cells in the lesions were evaluated by assessing proliferating cell nuclear antigen (PCNA) expression and silver-staining nucleolar organizer regions...

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Source

Identifiers

PMID: 9726818
DOI: 10.1002/(sici)1098-2744(199808)22:4<258::aid-mc7>3.0.co;2-f

Genes

PCNA
CGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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