Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transgenic shuttle vector assays for assessing oxidative B-cell mutagenesis in vivo.

Current topics in microbiology and immunology - 1 Jan 1999

Felix K, Kelliher K, Bornkamm G W, Janz S

Abstract excerpt

The recent development of transgenic mutagenicity assays provides new opportunities for evaluating mutagenic processes in vivo. To asses mutant frequencies in tissue B cells, we decided to take advantage of two such assays that utilize the transgenic shuttle vectors, lambda LIZ and pUR288. Our main interest in this research is to test two basic premises of inflammation-induced plasmacytoma development in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Bacteriophage lambda
Share to Genetic Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oxidation-Reduction

Share to Phagocytes

Share to Plasmacytoma

Share to Plasmids

Source

Identifiers

PMID: 10396077
DOI: 10.1007/978-3-642-60162-0_45

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transgenic shuttle vector assays for assessing oxidative B-cell mutagenesis in vivo.PMID 10396077Read ↗

Moderate hypermutability of a transgenic lacZ reporter gene in Myc-dependent inflammation-induced plasma cell tumors in mice.Semantic proximity Read ↗

The use of shuttle vectors for mutation analysis in transgenic mice and rats.Semantic proximity Read ↗

Use of transgenic mouse models for studying somatic mutations in aging.Semantic proximity Read ↗

Restricting activation‐induced cytidine deaminase tumorigenic activity in B lymphocytesSemantic proximity Read ↗

Immunogenic variants induced by mutagens: a mechanism for generating autoimmune responses to tumors.Semantic proximity Read ↗

Analysis of In Vivo Mutation in the Hprt and Tk Genes of Mouse Lymphocytes.Semantic proximity Read ↗

Analysis of spontaneous and induced mutation frequencies in transgenic mice using a lambda shuttle vector system.Semantic proximity Read ↗

Analysis of in vivo mutation in the hprt and tk genes of mouse lymphocytes.Semantic proximity Read ↗

Assessment of 1,3-butadiene mutagenicity in the bone marrow of B6C3F1 lacI transgenic mice (Big Blue): a review of mutational spectrum and lacI mutant frequency after a 5-day 625 ppm 1,3-butadiene exposure.Semantic proximity Read ↗

Frequency and spectrum of ENU-induced mutation in the Phi X174 transgene in mouse splenic lymphocytes and their significance to spontaneous transgenic rodent mutation frequencies.Semantic proximity Read ↗

Further characterization and validation of gpt delta transgenic mice for quantifying somatic mutations in vivo.Semantic proximity Read ↗

Molecular analysis of lacI mutants from transgenic fibroblasts exposed to 1,2-epoxybutene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.