Article
The use of shuttle vectors for mutation analysis in transgenic mice and rats.
Mutation research - 1 Jun 1994
Dycaico M J, Provost G S, Kretz P L, Ransom S L, Moores J C, Short J M
Abstract excerpt
The establishment in recent years of transgenic shuttle vector-based mutagenicity assays has provided improved systems for analysis of mutagenic and carcinogenic processes. Results in the mouse have stimulated the development of an alternate species suitable for mutation analysis and have increased our understanding of the existing models. A previously described shuttle vector (lambda LIZ), based on a lacI target...
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