The use of shuttle vectors for mutation analysis in transgenic mice and rats.

doi:10.1016/0027-5107(94)90257-7

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Article

The use of shuttle vectors for mutation analysis in transgenic mice and rats.

Mutation research - 1 Jun 1994

Dycaico M J, Provost G S, Kretz P L, Ransom S L, Moores J C, Short J M

Abstract excerpt

The establishment in recent years of transgenic shuttle vector-based mutagenicity assays has provided improved systems for analysis of mutagenic and carcinogenic processes. Results in the mouse have stimulated the development of an alternate species suitable for mutation analysis and have increas...

Topics

Animals
Animals, Genetically Modified
DNA Transposable Elements
Female
Gene Deletion
Genes, p53
Genetic Vectors
Germ Cells
Lac Operon
Liver
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Mice, Transgenic
Models, Genetic
Mutagenesis, Site-Directed
Mutagenicity Tests

Source

Open in PubMed

Identifiers

PMID: 7514720
DOI: 10.1016/0027-5107(94)90257-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7514720-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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