Article
The primary sex determination signal of Caenorhabditis elegans.
Genetics - 1 Jul 1999
Carmi I, Meyer B J
Abstract excerpt
An X chromosome counting process determines sex in Caenorhabditis elegans. The dose of X chromosomes is translated into sexual fate by a set of X-linked genes that together control the activity of the sex-determination and dosage-compensation switch gene, xol-1. The double dose of X elements in XX animals represses xol-1 expression, promoting the hermaphrodite fate, while the single dose of X elements in XO...
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