Article
X-chromosome-counting mechanisms that determine nematode sex.
Nature - 10 Jul 1997
Nicoll M, Akerib C C, Meyer B J
Abstract excerpt
Sex is determined in Caenorhabditis elegans by an X-chromosome-counting mechanism that reliably distinguishes the twofold difference in X-chromosome dose between males (1X) and hermaphrodites (2X). This small quantitative difference is translated into the 'on/off' response of the target gene, xol...
Topics
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Chromosome Mapping
- Disorders of Sex Development
- Gene Dosage
- Gene Expression Regulation
- Genes, Helminth
- Genes, Reporter
- Helminth Proteins
- Karyotyping
- Male
- Mutation
- RNA-Binding Proteins
- Sex Differentiation
- Transcription, Genetic
- X Chromosome