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Article

X-chromosome-counting mechanisms that determine nematode sex.

Nature - 10 Jul 1997

Nicoll M, Akerib C C, Meyer B J

Abstract excerpt

Sex is determined in Caenorhabditis elegans by an X-chromosome-counting mechanism that reliably distinguishes the twofold difference in X-chromosome dose between males (1X) and hermaphrodites (2X). This small quantitative difference is translated into the 'on/off' response of the target gene, xol-1, a switch that specifies the male fate when active and the hermaphrodite fate when inactive. Specific regions of X...

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PMID: 9217163
DOI: 10.1038/40669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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