The nuclear hormone receptor SEX-1 is an X-chromosome signal that determines nematode sex.

doi:10.1038/24164

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Article

The nuclear hormone receptor SEX-1 is an X-chromosome signal that determines nematode sex.

Nature - 12 Nov 1998

Carmi I, Kopczynski J B, Meyer B J

Abstract excerpt

Organisms in many phyla determine sexual fate by distinguishing one X chromosome from two. Here we use the model organism Caenorhabditis elegans to dissect such an X-chromosome-counting mechanism in molecular detail. In this nematode, several genes on the X chromosome called X signal elements com...

Topics

Amino Acid Sequence
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Chromosome Mapping
Disorders of Sex Development
Dosage Compensation, Genetic
Female
Gene Expression Regulation, Developmental
Genes, Helminth
Helminth Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Molecular Sequence Data

Mutation

Receptors, Cytoplasmic and Nuclear

Repressor Proteins

Sex Determination Processes

Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 9823896
DOI: 10.1038/24164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9823896-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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