Article
Analysis of human IgE epitope of Der f 2 with anti-Der f 2 mouse monoclonal antibodies.
Molecular immunology - 1 Jan 1999
Nishiyama C, Hatanaka H, Ichikawa S, Fukada M, Akagawa-Chihara M, Yuuki T, Yokota T, Inagaki F, Okumura Y
Abstract excerpt
Der f 2 is one of the major mite allergens recognized by human IgE antibodies of allergic patients. Using five anti-Der f 2 mouse monoclonal antibodies, human IgE epitopes of Der f 2 were analyzed. Among them, two monoclonal antibodies 15E11 and 13A4 inhibited the binding between Der f 2 and human IgE antibodies. To determine major IgE epitopes of Der f 2, epitopes for the monoclonal IgG antibodies were analyzed...
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