Article
Monoclonal antibody and ligand binding sites of the T cell erythrocyte receptor (CD2).
Nature - 1 Jan 2000
Peterson A, Seed B
Abstract excerpt
The human T cell erythrocyte receptor (CD2 antigen) allows thymocytes and mature T cells to adhere to thymic epithelium and target cells through a cell surface protein, LFA-3 (refs 1-6). Monoclonal antibodies recognizing CD2 can either block adhesion or, in certain combinations, induce an antigen...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antigens, Differentiation, T-Lymphocyte
- Binding Sites
- Cell Line
- Epitopes
- Humans
- Ligands
- Mutation
- Protein Binding