Article
Effects of amino acid variations in recombinant Der fII on its human IgE and mouse IgG recognition.
International archives of allergy and immunology - 1 Sept 1994
Nishiyama C, Yuuki T, Usui Y, Iwamoto N, Okumura Y, Okudaira H
Abstract excerpt
Amino acid sequencing of the major mite allergen Der fII purified from mite body extract revealed that it is a mixture of at least two variants. Substitutions were found only at positions in which amino acid variations were predicted from the nucleotide sequences of three cloned cDNAs. When cDNAs...
Topics
- Allergens
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antigens, Dermatophagoides
- Drug Stability
- Genetic Variation
- Glycoproteins
- Humans
- Immunoglobulin E
- Immunoglobulin G
- Mice
