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Article

Microsatellite instability is co-selectable with gene amplification in a mammalian mutator phenotype.

Anticancer research - 1 Jan 2000

Caligo M A, Ghimenti C, Sensi E, Piras A, Rainaldi G

Abstract excerpt

The effect of an unbalanced nucleotide pool on the stability of dinucleotide (CA)n microsatellite sequences was investigated in the mutator phenotype CSA7 clone isolated from Chinese hamster CHEF18 cell line. A series of clones isolated from CHEF18 and CSA7 cells and resistant to 6-thioguanine (TG) were shown to be stable at the three examined microsatellite loci. Furthermore, the clones isolated from CHEF18...

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PMID: 10368687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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