Article
dCTP misincorporation in a Chinese hamster mutator phenotype: the role of GGA genetic context.
Mutagenesis - 1 Jul 1996
Rainaldi G, Meneveri R, Mariani L, Ginelli E, Moretti A, Vatteroni L
Abstract excerpt
Clone CSA7 is a CHEF18 hamster cell line that shows an increased intracellular accumulation of dCTP. To localize the mutations that accumulate spontaneously in a functional gene of such a mutator phenotype, independent CSA7 mutants of the hypoxanthine-guanine phosphoribosyl transferase (hprt) gene were isolated and screened by a polymerase chain reaction-single strand conformation polymorphism technique....
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