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Article

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

Immunity - 1 May 1999

Radtke F, Wilson A, Stark G, Bauer M, van Meerwijk J, MacDonald H R, Aguet M

Abstract excerpt

Notch proteins are cell surface receptors that mediate developmental cell specification events. To explore the function of murine Notch1, an essential portion of the gene was flanked with loxP sites and inactivation induced via interferon-regulated Cre recombinase. Mice with a neonatally induced...

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Identifiers

PMID: 10367900
DOI: 10.1016/s1074-7613(00)80054-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10367900-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Deficient T cell fate specification in mice with an induced inactivation of Notch1.PMID 10367900Read ↗

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