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Article

Regulation of T cell fate by Notch.

Annual review of immunology - 1 Jan 1999

Robey E

Abstract excerpt

The transmembrane receptor Notch participates in diverse cell fate decisions throughout embryonic development. Notch receptors and their ligands are expressed in the mammalian thymus, raising the possibility that Notch could regulate T cell fate decisions. Expression of a constitutively activated form of Notch in developing thymocytes causes thymocytes normally destined for the CD4 lineage to adopt the CD8...

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Identifiers

PMID: 10358760
DOI: 10.1146/annurev.immunol.17.1.283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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