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Article

Normal immune system development in mice lacking the Deltex-1 RING finger domain.

Molecular and cellular biology - 1 Feb 2005

Storck Sébastien, Delbos Frédéric, Stadler Nicolas, Thirion-Delalande Catherine, Bernex Florence, Verthuy Christophe, Ferrier Pierre, Weill Jean-Claude, Reynaud Claude-Agnès

Abstract excerpt

The Notch signaling pathway controls several cell fate decisions during lymphocyte development, from T-cell lineage commitment to the peripheral differentiation of B and T lymphocytes. Deltex-1 is a RING finger ubiquitin ligase which is conserved from Drosophila to humans and has been proposed to be a regulator of Notch signaling. Its pattern of lymphoid expression as well as gain-of-function experiments suggest...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15684394
DOI: 10.1128/MCB.25.4.1437-1445.2005
PMCID: PMC548011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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