Article
Angiotensin II-induced modulation of rat mesangial cell phenotype.
Radiation research - 1 Jun 1999
Zhang X, O'Malley Y, Robbins M E
Abstract excerpt
Inhibition of angiotensin II (AII) can ameliorate the severity of experimental radiation nephropathy. To determine the ability of AII to modulate mesangial cell phenotype, primary cultures of rat mesangial cells (passage number 6-11) were placed in serum-free medium 24 h prior to addition of AII (10(-9)-10(-5) M); control cells received serum-free medium alone. Cells were maintained in serum-free medium for a...
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