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Article

High-resolution mapping of crossovers in human sperm defines a minisatellite-associated recombination hotspot.

Molecular cell - 1 Aug 1998

Jeffreys A J, Murray J, Neumann R

Abstract excerpt

Little is known about the fine-scale distribution of meiotic crossovers in human chromosomes. Methods have therefore been developed for detecting and mapping recombination products directly in human sperm DNA. Analysis of crossovers adjacent to the GC-rich minisatellite MS32, which is known to mutate by conversion and crossover within the repeat array, revealed an intense and highly localized recombination...

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Identifiers

PMID: 9734365
DOI: 10.1016/s1097-2765(00)80138-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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