Article
Analysis of select folate pathway genes, PAX3, and human T in a Midwestern neural tube defect population.
Teratology - 1 May 1999
Trembath D, Sherbondy A L, Vandyke D C, Shaw G M, Todoroff K, Lammer E J, Finnell R H, Marker S, Lerner G, Murray J C
Abstract excerpt
Neural tube defects (NTDs) are a common birth defect, seen in approximately 1/1,000 births in the United States. NTDs are considered a complex trait where several genes, interacting with environmental factors, create the phenotype. Using a Midwestern NTD population consisting of probands, parents, and siblings from Iowa, Minnesota, and Nebraska, we analyzed a range of candidate genes, including...
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