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Article

Genetic Risk Factors for Folate-Responsive Neural Tube Defects.

Annual review of nutrition - 21 Aug 2017

Molloy Anne M, Pangilinan Faith, Brody Lawrence C

Abstract excerpt

Neural tube defects (NTDs) are the most severe congenital malformations of the central nervous system. The etiology is complex, with both genetic and environmental factors having important contributions. Researchers have known for the past two decades that maternal periconceptional use of the B vitamin folic acid can prevent many NTDs. Though this finding is arguably one of the most important recent discoveries...

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PMID: 28628360
DOI: 10.1146/annurev-nutr-071714-034235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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