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Article

Analysis of the human folate receptor beta gene for an association with neural tube defects.

Molecular genetics and metabolism - 1 Jun 2003

O'Leary Valerie B, Mills James L, Kirke Peadar N, Parle-McDermott Anne, Swanson Deborah A, Weiler Andrea, Pangilinan Faith, Conley Mary, Molloy Anne M, Lynch Miriam, Cox Christopher, Scott John M, Brody Lawrence C

Abstract excerpt

The folate receptor beta (FRbeta) gene encodes a receptor that binds and transports 5-methyltetrahydrofolate. FRbeta polymorphisms may potentially alter folate delivery and are likely candidates for an association with neural tube defect (NTD) risk. To look for association between FRbeta polymorphisms we studied NTD-affected children and their parents (254 triads) recruited throughout Ireland and a control...

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PMID: 12809644
DOI: 10.1016/s1096-7192(03)00075-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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