The timing of XIST replication: dominance of the domain.

doi:10.1093/hmg/8.6.1085

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Article

The timing of XIST replication: dominance of the domain.

Human molecular genetics - 1 Jun 1999

Gartler S M, Goldstein L, Tyler-Freer S E, Hansen R S

Abstract excerpt

Contiguous replicons are coordinately replicated and may be organized in temporal-spatial domains with early replication domains containing expressed genes and late ones carrying silent genes. XIST is silent on the active, early replicating X chromosome and expressed from the inactive, late replicating homolog. These circumstances potentially deviate from the aforementioned generalization and make studies of...

Topics

Alleles
Cell Cycle
Cells, Cultured
DNA Replication
Dosage Compensation, Genetic
Female
Fibroblasts
Genes, Dominant
Humans
In Situ Hybridization, Fluorescence
Male
RNA, Long Noncoding
RNA, Untranslated
Time Factors
Transcription Factors
X Chromosome

Source

Open in PubMed

Identifiers

PMID: 10332041
DOI: 10.1093/hmg/8.6.1085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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