Article
The XIST locus replicates late on the active X, and earlier on the inactive X based on FISH DNA replication analysis of somatic cell hybrids.
Somatic cell and molecular genetics - 1 Sept 1995
Torchia B S, Migeon B R
Abstract excerpt
We have recently reported results of DNA replication analysis of three X-linked loci (FRAXA, F8C and XIST) on the X chromosomes in male and female fibroblasts using fluorescence in situ hybridization (FISH) (1). Although our findings that XIST replicates later on the active X than on the inactive...
Topics
- Animals
- Cells, Cultured
- Chromosome Mapping
- DNA Replication
- Fibroblasts
- Genetic Markers
- Genetic Variation
- Guanosine Diphosphate
- Humans
- Hybrid Cells
- In Situ Hybridization, Fluorescence
- Male
- Mice
- RNA, Long Noncoding
- RNA, Untranslated
- Skin
- Transcription Factors
- X Chromosome