Article
Role of p53 gene mutation in tumor aggressiveness of intracranial meningiomas.
Journal of Korean medical science - 1 Apr 1999
Cho H, Ha S Y, Park S H, Park K, Chae Y S
Abstract excerpt
The mutations that occur in the p53 tumor suppressor gene have been studied in various human malignant tumors. However, little is known about this gene in meningiomas. To investigate the relationship and frequency of p53 gene mutations, the p53 polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) and immunohistochemical study were performed on the 41 intracranial meningiomas (21...
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