Article
Methylation of p14(ARF) gene in meningiomas and its correlation to the p53 expression and mutation.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2004
Amatya Vishwa Jeet, Takeshima Yukio, Inai Kouki
Abstract excerpt
We have previously reported the statistically significant correlation of immunohistochemical expression of MIB-1 and p53 proteins among benign, atypical, and anaplastic meningiomas and p53 protein expression was high in atypical and anaplastic meningiomas. In the present study, we analyzed 22 cases of meningiomas for mutation of p53 gene in its spectrum of exon 5 to 8 using automated genetic analyzer. We did not...
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