Article
Integrative genomic analysis identifies CCNB1 and CDC2 as candidate genes associated with meningioma recurrence.
Cancer genetics - 1 Oct 2011
Bie Li, Zhao Gang, Ju Yan, Zhang Bo
Abstract excerpt
Meningiomas are a common type of primary central nervous system tumor. Patients with atypical meningioma are difficult to treat and their disease often recurs. The aim of this study was to examine the role of CCNB1 and CDC2 as factors in recurrent meningiomas. A total of 37 sporadic meningioma samples were collected after surgery. The messenger RNA (mRNA) levels of the biomarkers CCNB1, CDC2, and MKI67 were...
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