Detection of <i>TP53</i> gene mutation in human meningiomas: A study using immunohistochemistry, polymerase chain reaction/single‐strand conformation polymorphism and dna sequencing techniques on paraffin‐embedded samples

Abstract excerpt

Mutations in the TP53 tumor suppressor gene have been studied in different types of brain tumors. Little is known about this genetic event in human meningioma, a mostly benign tumor. To investigate the frequency of TP53 gene mutations in human tumors derived from meningeal tissues, paraffin-embedded tissues from 30 cases (including 2 malignant and 4 atypical meningiomas, as well as 2 hemangioblastomas and 3...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bone Tumor Diagnosis and Treatments
• Share to Head and Neck Surgical Oncology