Article
The role of a single nucleotide polymorphism of the matrix metalloproteinase-1 gene promoter region in invasion and prognosis of meningiomas.
Turkish neurosurgery - 1 Jan 2014
Efendioglu Mustafa, Basaran Recep, Bayrak Omer Faruk, Isik Nejat, Kaner Tuncay, Sahin Fikrettin, Guclu Bulent, Elmaci Ilhan
Abstract excerpt
AIM: The matrix metalloproteinase (MMP) enzyme family has been shown to be active in tumorigenesis and tumor progression. In this study, we analyzed the prevalence of a guanine insertion in the MMP-1 gene promoter region in meningiomas and its effect on invasion and prognosis. MATERIAL AND METHODS: The study was performed with 33 meningioma patients. We also included 33 healthy patients in the study as a control...
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