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Article

Polymorphisms and DNA methylation of gene TP53 associated with extra-axial brain tumors.

Genetics and molecular research : GMR - 6 Jan 2009

Almeida L O, Custódio A C, Pinto G R, Santos M J, Almeida J R W, Clara C A, Rey J A, Casartelli C

Abstract excerpt

The p53 tumor suppressor gene is the most frequently mutated gene in human cancer; this gene is mutated in up to 50% of human tumors. It has a critical role in the cell cycle, apoptosis and cell senescence, and it participates in many crucial physiological and pathological processes. Polymorphism...

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PMID: 19224462
DOI: 10.4238/vol8-1gmr518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19224462-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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