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Article

Presenilin 1 polymorphism associated with Alzheimer's disease in apolipoprotein E4 carriers.

Dementia and geriatric cognitive disorders - 1 Jan 2008

Martínez-García Ana, Aldudo Jesús, Recuero María, Sastre Isabel, Vilella-Cuadrada Elisabet, Rosich-Estragó Marcel, Frank Ana, Valdivieso Fernando, Bullido María J

Abstract excerpt

Mutations of presenilin 1 (PSEN1) are associated with monogenic Alzheimer's disease (AD); polymorphisms at this gene may therefore be associated with the sporadic form of the disease. In fact, recent meta-analyses and whole-genome association studies indicate PSEN1 as one of the few genes significantly associated with AD risk. Several polymorphisms have been analyzed in PSEN1. The present work examined the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18957849
DOI: 10.1159/000165685

Genes

PSEN1
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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