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Article

Polymorphism of the regulatory region of the presenilin-2 gene in sporadic Alzheimer's disease: a case-control study.

Journal of the neurological sciences - 15 Jan 2006

Quan Wenxiang, Yasuda Minoru, Hashimoto Mamoru, Yamamoto Yasuji, Ishii Kazunari, Kazui Hiroaki, Mori Etsuro, Kakigi Tatsuya, Maeda Kiyoshi

Abstract excerpt

OBJECTIVE: presenilin-2 is one of the causative genes for familial Alzheimer's disease, and the apolipoprotein E epsilon4 allele is a major genetic risk factor for late-onset and sporadic early-onset Alzheimer's disease. Polymorphism of the regulatory region of presenilin-2 has recently been reported to be associated with sporadic Alzheimer's disease in a Russian population. The purpose of this study was to...

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Source

Identifiers

PMID: 16233903
DOI: 10.1016/j.jns.2005.09.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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