Article
Association between presenilin 1 intronic polymorphism and late onset Alzheimer's disease in the North Chinese population.
Brain research - 20 Oct 2006
Jia Longfei, Zhou Chunkui, Lv Haiyan, Wang Weishan, Ye Jing, Zhang Xiaojun, Zhou Weidong, Xu Jiangtao, Wang Lingling, Jia Jianping
Abstract excerpt
The association between presenilin 1 intronic polymorphism (rs165932) and late onset Alzheimer's disease (LOAD) has been a matter of controversy. Within China, varied results have been reported. Therefore, we collected a large sample from the North Chinese population to test the association of the PS1 polymorphism with LOAD. AD patients (467 total, mean age=75.3+/-7.3, age at onset=70.2+/-5.1) and age-matched...
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