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Article

C-terminal domains of human translation termination factors eRF1 and eRF3 mediate their in vivo interaction.

FEBS letters - 22 Jan 1999

Merkulova T I, Frolova L Y, Lazar M, Camonis J, Kisselev L L

Abstract excerpt

At the termination step of protein synthesis, hydrolysis of the peptidyl-tRNA is jointly catalysed at the ribosome by the termination codon and the polypeptide release factor (eRF1 in eukaryotes). eRF1 forms in vivo and in vitro a stable complex with release factor eRF3, an eRF1-dependent and ribosome-dependent GTPase. The role of the eRF1-eRF3 complex in translation remains unclear. We have undertaken a...

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PMID: 9928949
DOI: 10.1016/s0014-5793(98)01669-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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C-terminal domains of human translation termination factors eRF1 and eRF3 mediate their in vivo interaction.PMID 9928949Read ↗

Structural insights into eRF3 and stop codon recognition by eRF1.Semantic proximity Read ↗

The C-terminus of eRF1 defines a functionally important domain for translation termination in Saccharomyces cerevisiae.Semantic proximity Read ↗

N-terminal region of Saccharomyces cerevisiae eRF3 is essential for the functioning of the eRF1/eRF3 complex beyond translation termination.Semantic proximity Read ↗

N-terminal extension of Saccharomyces cerevisiae translation termination factor eRF3 influences the suppression efficiency of sup35 mutations.Semantic proximity Read ↗

Eukaryotic release factor 3 is required for multiple turnovers of peptide release catalysis by eukaryotic release factor 1.Semantic proximity Read ↗

Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe.Semantic proximity Read ↗

Identification of translational release factor eRF1a binding sites on eRF3 in Euplotes octocarinatus.Semantic proximity Read ↗

A genetic approach for analyzing the co-operative function of the tRNA mimicry complex, eRF1/eRF3, in translation termination on the ribosome.Semantic proximity Read ↗

The Translation Termination Factor eRF3 Interacts Sequentially with eRF1 and ABCE1 on the RibosomeSemantic proximity Read ↗

The role of N-terminal domain of translational release factor eRF3 for the control of functionality and stability in S. cerevisiae.Semantic proximity Read ↗

Molecular dissection of translation termination mechanism identifies two new critical regions in eRF1.Semantic proximity Read ↗

Two-step model of stop codon recognition by eukaryotic release factor eRF1.Semantic proximity Read ↗

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