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Article

Viable nonsense mutants for the essential gene SUP45 of Saccharomyces cerevisiae.

BMC molecular biology - 10 Feb 2003

Moskalenko Svetlana E, Chabelskaya Svetlana V, Inge-Vechtomov Sergei G, Philippe Michel, Zhouravleva Galina A

Abstract excerpt

BACKGROUND: Termination of protein synthesis in eukaryotes involves at least two polypeptide release factors (eRFs) - eRF1 and eRF3. The highly conserved translation termination factor eRF1 in Saccharomyces cerevisiae is encoded by the essential gene SUP45. RESULTS: We have isolated five sup45-n (n from nonsense) mutations that cause nonsense substitutions in the following amino acid positions of eRF1: Y53 -->...

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Identifiers

PMID: 12589713
DOI: 10.1186/1471-2199-4-2
PMCID: PMC150568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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